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Her groundbreaking work discovered that a protein that is critical for cell survival has two distinct mitochondrial localizations with disparate functions, linking its anti-apoptotic role to a previously unrecognized role in mitochondrial respiration and maintenance of the mitochondrial structure

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Decrease in OP requires excessive solute uptake, to create sufficient turgor for cell growth and elongation 15,96

CXC-chemokine ligand 12 (CXCL12) also has a role in EAE and MS pathogenesis as it mediates T cell arrest on brain ECs and the basolateral release of inflammatory cells 138140