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Ammonia Metabolism Biochemistry and Physiology The major source of circulating ammonia is the GI tract
In addition, dysregulated mitochondrial biogenesis and excessive ATP release under oxidative conditions act as damage-associated molecular patterns (DAMPs), activating inflammasomes and enhancing chemotactic signals for immune cells like CD8 + T cells 67
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J Clin Invest 130, 64096416 (2020)
