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Thus, it appears that 6-MAM plays a major role in producing the brain hypoxia associated with heroin overdose [137]

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Intriguingly, a recent study found that self-destructive and multienzymatically active copper-based nanoparticles can affect the antioxidant defense mechanism of cancer cells by inhibiting the nuclear factor-erythroid 2-related factor 2-quinone oxidoreductase 1 signaling pathway

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