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Rev Med Chil 145(12):15791587 Oo KM (n.d.) Causes, symptoms and prevention of thyroid diseases

Collins suspected these side effects occurred when antibiotics triggered oxidative stress a condition in which cells produce chemically reactive oxygen molecules that damage the bacterias DNA and enzymes, as well as the membrane that encloses the cell

Thus, TNBS promotes two independent mechanisms of injury, GSH depletion and ROS generation, both being required for the manifestation of mucosal injury as GSH limitation renders intestine susceptible to the TNBS-induced ROS overgeneration

Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study