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Description
2021;71:e12716
Erastin, as a small-molecule ferroptosis inducer, works by inhibiting the system Xc transporter-an amino acid antiporter responsible for exchanging extracellular cystine for intracellular glutamate (11)-leading to depletion of intracellular glutathione (GSH), indirectly inactivating glutathione peroxidase 4 (GPX4), and ultimately triggering ferroptosis (12)
889 Inhibition of the Wnt signal hinders osteogenic differentiation by affecting the Smad and MAPK signaling pathways
Enhances athletic performance and weight loss
