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If the accumulation of hydrogen peroxide is not limited, it can diffuse to the cytosol or participate in a chain of reactions that generate more reactive free radicals, such as hydroxyl radical, which can oxidize mitochondrial components (proteins, lipids, and DNA)
CDAI values of 150 and below are associated with remission, and values above indicate active disease (150 219 points - a mild exacerbation, moderate 220 450, above 450 points as severe) (35)
Suicide is as a paramount global health concern that demands efficacious preventive strategies
doi:10.3390/ijms24065474 195
