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Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

These peripheral and central deficits can include severe gastrointestinal lesions, intracranial (superior sagittal sinus) hypertension, brain swelling and lesions, portal and caval hypertension, aortic hypotension, peripheral and central thrombosis, inferior caval vein and superior mesenteric vein congestion, azygos vein failure, electrocardiogram (ECG) disturbances, and heart, lung, liver, and kidney lesions (Vukojevic et al., 2018

5 Patient safety for marginalised groups in primary care is a growing empirical field

Future research should focus on improving their stability, bioavailability, and delivery systems to fully harness their clinical potential in regenerative medicine