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24 hours: Transaminitis and possibly coagulopathy

Holmer et al., 2021).These dietary regimens alleviate hepatic lipids by lowering body weight and insulin resistance (Volek et al., 2009

Expression matrices were merged using ComBat-seq 45 and normalized with a variance-stabilizing transformation

425,426 In the heart tissue of conditional frataxin knockout mice, increased mRNA levels of MFRN2, SEC15L1, and TFR1 and decreased mRNA levels of FPN1 indicate an activated response to cytoplasmic iron deficiency and increased mitochondrial iron input
