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However, it is important to note that this medication is highly controlled because of its teratogenic at all therapeutic doses 5 and because the serious side effects it may cause 6

The measurement of biomarkers in conjunction with a drug treatment could be important both during drug development and clinical implementation after marketing approval
Some new research methods, such as those of network pharmacology, can be used to predict the effective composition of the plant and the mechanisms behind its pharmacological activities

Molecular Aspects of Medicine, 32 (46), 305315
