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Magnetic resonance imaging (MRI) in September 2016 revealed bilateral degeneration of the forearm proximal tendons and degenerative changes of the neck muscles, with progression of these changes shown in the study of March 2018 (Figure 1)

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Pharmacokinetic profiles for the compound place its plasma half-life in the neighborhood of 45 minutes after parenteral administration in animal models, which informs typical dosing intervals in published experiments
