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These symptoms Symptoms of nicotine withdrawal Common symptoms of nicotine withdrawal include: anger, frustration, and irritability anxiety and depression difficulty concentrating and restlessness nicotine cravings headaches and dizziness insomnia Nicotine withdrawal symptoms are usually worst during the first week after smoking cessation

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Other components of CS have been shown to regulate neurotransmitter release, activate receptors, and inhibit monoamine oxidase, ultimately leading to an antidepressant effect [92]

"There's no question that e-cigarettes deliver fewer [toxic substances] than conventional cigarettes, but the question of how much less is still not clear," says Stanton Glantz, director of the Centre for Tobacco Control Research and Education at the University of California at San Francisco