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Am J Epidemiol

All were odorless except one, he wrote, which smelled like green apples. Perfetti synthesized 30 different nicotine salt concoctions, then heated them like a smoker would in pursuit of the maximum release of nicotine. He also tested the salts ability to dissolve into a liquid a trait that would decades later become central to vaping products like Juul

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The agency determined that the vast majority of manufacturers had failed to show that possible benefits to adult smokers looking to quit outweighed the threat posed to young people