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Believing that asthma was more likely to be caused by spasmodic constriction of the bronchi than by the accumulation of mucus, Laennec recommended a variety of anti-spasmodics, including opium, belladonna, stramonium, tobacco, hyoscyamus and coffee

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In beer production, a 'diacetyl rest' is sometimes performed, where the temperature is raised slightly for two or three days after fermentation to allow yeast to absorb diacetyl