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Additionally, cigarette smoke exposure in a COPD mouse model altered the intestinal microbiome, with changes in diversity, composition, and metabolism, including lysine degradation and phenylalanine metabolism

In March 2023, the FDA issued a sales ban (MDO) for two menthol e-cigarette products of the Vuse Solo brand under Reynolds American Company, including "Vuse Menthol 4.8% G1" and "Vuse Menthol 4.8% G2"

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Nicotine is highly addictive, which is one of the main reasons tobacco products have become so widely used and difficult to quit