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Charleston Animal Society is teaming up with researchers at MUSC to help smokers kick the habit

In a study undertaken to determine the effect of smoking on stomach acid secretion, it was found that cigarette smoking decreased gastric acid secretion and gastric mucosal blood flow

Bibcode:1989ArTox

If you look through historical archives of the 20th century, you'll find that the cigarette holder was a female fashion accessory akin to what hats were for men
