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Thus, a buildup of O 2 and H 2 O 2 is still a major contributor to the accumulation of oxidative DNA damage because both of these two ROS can be converted to OH which, in turn, can inflict damage on DNA [22, 23]
this anecdotal evidence is backed up by the data on tobacco usage
However, a decreasing tendency was observed in benign breast adenoma (female mice fed with tobacco), malignant skin basal cell carcinoma (female mice fed with water extract of tobacco blend), and benign thyroid follicular cell adenoma (male rats fed with water extract of tobacco blend)
Benet, S
