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Based on toxicology data, consumer research, and public health modeling, though, the FDA gave a Modified Risk Tobacco Product (MRTP) order to 10 Zyn flavors at each of two strengths3 milligrams and 6 milligrams

Congress created a special rule for exposure modification orders, allowing FDA to authorize such claims where long-term epidemiological evidence may not yet be available, but the available evidence supports that the product is reasonably likely to reduce morbidity or mortality, substantially reduce exposure to harmful substances, and not mislead consumers into believing that the product has been shown to reduce disease risk unless that has been demonstrated

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