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The SURMOUNT-4 trial showed that people who continued tirzepatide after their initial plateau lost an additional 5.5 percent of body weight, while those switched to placebo regained 14 percent

The process takes a few weeks to complete

Mounting evidence suggests that GLP-1 RAs have benefits beyond reducing blood glucose that include improving kidney function in people living with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), a common microvascular complication of T2DM

Instead, two recent works have provided compelling histological evidence that nerve fibers do not truly contact enterochromaffin cells in the mouse colon 24,42