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Indeed, nicotine inhalation (0-64 mg/ml) showed a dose-dependent increase in the amount of coughing and airway obstruction in non-smokers, which may be a consequence of the stimulation of afferent nerve endings in the bronchial mucosa by nicotine, which in turn triggers parasympathetic cholinergic pathways leading to bronchoconstriction [62]
E-cigarettes first appeared in the U.S
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As a result, oxygen is not able to travel adequately to various organs
