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Description
Heterogeneous findings may be the product of cross-sectional designs with modest-to-moderate sample sizes, between-study variability in participant attributes (e.g., varying age ranges, smoking histories, sex ratios, or other sociodemographic characteristics), and/or methodological differences in MRI acquisition or data analysis parameters (e.g., smoothing, registration techniques, or normalization templates)

Since these organs come into contact with the cancer-causing chemicals in cigarette smoke, this makes sense.
The individual behavior of each of the 82 mice could be defined as a weighted combination of these three extrema in a ternary plot (Fig

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