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In this study, ISGlobal researcher Juan Ramn Gonzlez and his team evaluated the effects of tobacco, alcohol and marijuana on DNA methylation throughout the entire genome, with the idea of identifying metabolic pathways that could be affected and that could explain the association between these substances and neurological and cardiovascular disorders

First, although the GBD data cover a broad spectrum of countries and regions, biases in data collection and reporting may persist particularly in low-income settings potentially introducing systematic error into our estimates

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