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According to the American Lung Association, it may also contain formaldehyde and acrolein

Conclusion Though research on e-cigarettes is rapidly expanding, the relative newness of the product means that long-term studies on the health effects of e-cigarette use are not yet available

[1] However, researchers at Johns Hopkins University analyzed the vape clouds of popular brands such as Juul and Vuse, and found "nearly 2,000 chemicals, the vast majority of which are unidentified." [2] The aerosol of e-cigarettes is generated when the e-liquid comes in contact with a coil heated to a temperature of roughly 100250 C (212482 F) within a chamber, which is thought to cause pyrolysis of the e-liquid and could also lead to decomposition of other liquid ingredients

The introduction of high-nicotine delivery systems such as JUUL transformed the e-cigarette landscape and increased the addiction potential for young people