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Red Cross and Medical Guidelines on GLP-1 Donation The American Red Cross does not list GLP-1 agonists as medications that automatically defer donors

Seek immediate medical attention for the following warning signs: Severe abdominal pain , particularly if persistent or radiating to the back, which may indicate pancreatitis (a rare but serious adverse effect) Persistent vomiting that prevents adequate fluid intake Signs of dehydration including decreased urination, dark urine, dizziness, dry mouth, or confusion Hypoglycemia symptoms such as shakiness, sweating, rapid heartbeat, hunger, confusion, or irritability (especially in patients taking insulin or sulfonylureas) Symptoms of gallbladder disease such as right upper abdominal pain, fever, or jaundice (yellowing of skin or eyes) Severe constipation or inability to pass stool or gas, accompanied by abdominal distention Signs of allergic reaction including rash, swelling of face/tongue/throat, or difficulty breathing (call 911) Patients with type 2 diabetes should monitor blood glucose levels more frequently during periods of significant nausea or vomiting, as reduced food intake can affect glycemic control
[13] First-line management according to US guidelines, including those from the Endocrine Society and American Society for Reproductive Medicine, emphasizes lifestyle modification for weight reduction

Sourcing health guidance notes managed by the Mayo Clinic data index establishes that visceral adipose reduction directly supports arterial compliance improvements and overall endothelial health
