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However, beyond such specific, time-limited scenarios, both clinical evidence and guidelines state that GLP-1 drugs should not be used in the short term if your goal is lasting weight loss and health risk reduction

Reducing from 12mg to 9mg might resolve symptoms while maintaining substantial weight loss (26.4% at 9mg vs 28.7% at 12mg)

Beyond the Shot is a 45-page, dietitian-written guide that gives you a simple, realistic way to eat while on tirzepatide so you can stay nourished, consistent, and confident

In a study of semaglutide efficacy, the average reduction in weight from baseline was 10.2%, but 4.9% of patients achieved over 25% reduction from baseline, and 32.2% achieved less than a 5% reduction from baseline or even weight gain 5