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Still today, individuals with diabetes have an approximately two-fold increased risk of all-cause mortality than those without diabetes [3]
The ESSENCE trial will provide valuable data on the maintenance of histological benefits over 240 weeks of continuous treatment, but long-term extension studies and off-treatment follow-up protocols are needed to characterize rebound kinetics
As GLP-1RAs become more commonly used, clinicians need to monitor for AV dermatological side effects while planning suitable treatment approaches for patients who develop this condition