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Depression is not commonly reported, though rare cases have prompted ongoing safety reviews

Since alcohol use is related to both cannabis use and suicides, it may be the case that these findings are linked, but more work is needed to know for sure

Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women

Research specifically on this modified schedule is limited, but the pharmacology suggests it should preserve most benefits given GHs downstream effects through IGF-1