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The experts agreed that the choice between sequential and combined therapy largely depends on patient factors such as cardiovascular risk, stages of chronic kidney disease, comorbidities, body weight, and HbA1c levels

These findings suggest that titrating the dose can improve the drugs tolerability and support better adherence to the treatment regimen

doi: 10.1001/jama.2021.23619 [DOI] [PMC free article] [PubMed] [Google Scholar] 107.Kapoor I, Sarvepalli SM, DAlessio D, Grewal DS, Hadziahmetovic M
