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Those are the exact same molecules that drive rheumatoid arthritis
25 Gly 35,37 Substitution of Gly 35 for Aib, together with introduction of Aib at position 8, resulted in a potent analog called taspoglutide ( 3 )

The LDL receptor family includes the LDL receptor, LDLR-related protein 1 (LRP1), the very-low-density lipoprotein receptor (VLDLR), megalin (LRP2), LRP4, and LRP1b

The expression of resistin is upregulated by androgens, therefore there is a positive association between hyperandrogenism and high levels of resistin in PCOS patients
