lilly retatrutide trial clinical done! Now onto Zep! : r/Zepbound Eli Lilly and Company's Retatrutide
Description
Hepatology 2010;51:1584-92.ArticlePubMedPMC 64
Some GLP-1 analogues may influence glutamatergic and GABAergic pathways, potentially contributing to therapeutic effects in conditions such as epilepsy, autism spectrum disorders, and addiction, although further validation is required
As of the time of writing, retatrutide does not have a UK marketing authorisation
Based on rats studies, they also proposed the theory of the foregut exclusion hypothesis which suggests that delivery of nutrients to proximal small intestine leads to a release of a pro-diabetic factor, which is over secreted in diabetics [32]
