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GLP-1 is a hormone that is released by the intestines after eating

Resources We Trust Cleveland Clinic: Ozempic Babies: How GLP-1 Agonists Affect Fertility Mayo Clinic: New Study Links Combination of Hormone Therapy and Tirzepatide to Greater Weight Loss After Menopause

All these changes probably contribute to a more sustained if not more potent effect on glucose and lipid metabolism than mere calorie restriction
