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Degenerative changes were also detected in the subcommissural organ, median eminence of the hypothalamus, and tanycytes of the third ventricle
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The October 2023 research comparing tirzepatide and semaglutide also noted that the highest dose of tirzepatide came with the highest increased risk for nausea, vomiting and diarrhea, compared to the placebo group and those using semaglutide
