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[DOI] [PMC free article] [PubMed] [Google Scholar] [220].Kupersmith MJ, Gamell L, Turbin R, Peck V, Spiegel P, Wall M (1998)

This helps identify whether specific side effects are medication-specific or transition-specific

In SURMOUNT-1 (72 weeks), tirzepatide produced mean reductions of 15%, 19.5% and 20.9% at the 5, 10 and 15 mg doses versus 3.1% on placebo, and 90.9% of the 15 mg group lost at least 5% of starting weight

This is problematic as patients with raised ICP and IIH have existent clinically relevant cognitive deficits and drug therapy which exacerbates cognitive function further compromises cognition
