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Yan M, et al
Because thermoneutrality minimizes the contribution of non-shivering thermogenesis to whole-body energy expenditure and because non-shivering thermogenesis requires functional brown adipose tissue (BAT) [775], these data imply a contribution of endogenous GLP-1R signaling to the control of energy expenditure, at least in diet-induced obese mice, by regulating BAT activity
So while at first glance Mounjaro might seem like the obvious choice, its really not that simple
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