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As more healthy individuals seek AOM prescriptions for cosmetic or preventive reasons, insurers must consider how to interpret such use in underwriting and build an understanding of the nuanced, evolving interplay among pharmacologic intervention, lifestyle behaviors, and long-term outcomes
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The preventative benefits seem to be facilitated by reduced lipogenesis, increased autophagy, enhanced insulin signalling, and regulation of the FXR/RXR and LXR/RXR pathways (Ma et al
