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Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

After 4 h of fasting, 812-week-old wild-type mice were subcutaneously injected with liraglutide (400 g/kg body weight) or saline and, 2 h later, were dissected under inhalation anesthesia with isoflurane

Semaglutide belongs to a class of therapies called GLP-1 receptor agonists

Keeping a food and hunger diary: Tracking what you eat alongside hunger ratings can help identify patterns for example, whether hunger spikes at particular times of day or in response to specific triggers