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This effect was not species specific as a 5% solution of PGN in drinking water reduced histamine-induced gastric lesions both prior to and after histamine injections in Guinea pigs, though PGN intake prior to induction of the lesions provided better protection (Anderson and Soman 1965 Anderson, W., and P
In addition, regulatory bodies are becoming more supportive of new therapies, which may further accelerate the approval process for GLP 1 analogues

The problem is that research into proper dosing for sublingual use is not available

Lantus Prescribing Information 3
