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In these tissues, they perform several functions: phagocytosing and degrading foreign cells and harmful substances like oxidized LDL (ox-LDL), secreting pro-inflammatory cytokines, and differentiating into diverse immune cell types, such as inflammatory dendritic cells (DCs), macrophages, or foam cells [116,117,118]

Gastrointestinal adverse effects, initially viewed as limiting, were ultimately managed through dose titration and formulation design

E., Cooper, M
