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Nuclear factor kappa B (NF-B), NH2-terminal Jun kinases, and p53 MAPK are transcriptionally regulated pathways that have been considered one of the most important stress-signaling pathways, and oxidative stress plays a role in the development of type 2 diabetes mellitus through their involvement (14)

[DOI] [PubMed] [Google Scholar] 71.Dupre J., Ross S.A., Watson D., Brown J.C

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STEP UP: higher dose exploration The STEP UP trial investigated a higher dose of 7.2 mg weekly, three times the standard 2.4 mg dose