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Description
2018The incretin hormone GIP is upregulated in patients with atherosclerosis and stabilizes plaques in ApoE(-/-) mice by blocking monocyte/macrophage activation
In comparison to other antihyperglycaemic agents, DPP-4 inhibitors lowered total cholesterol slightly more than other agents (total cholesterol 0.18 [0.29

In addition, the presence of major pharmaceutical companies and ongoing innovation in drug development and delivery technologies have boosted North Americas leadership position in this space

The FDA decision is anticipated in 3Q2025
