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Among the orexigenic hormones, an elevated level of ghrelin has been observed in children and adults with PWS [34]

Conclusion An increase in CV awareness and CV risk screening is expected to lead to a greater adoption of medications with CV benefits, further reducing morbidity as well as mortality among patients with T2D

Proposed mechanisms include reduced postprandial glucose excursions, potentially through delayed glucose absorption and modest increases in endogenous GLP-1 secretion, though human evidence remains limited and of low certainty

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