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Description
Clinical manifestations of B12 deficiency are diverse and can affect multiple organ systems
The selected fragments were then linked together in the liquid-phase peptide synthesis (LPPS) using a plug-flow reactor (PFR) in a four-step process [64]

Because the concentration is high, injection volumes stay small

The typical supplementation protocol involves a loading phase of 20 grams daily (divided into four doses) for 5-7 days, followed by a maintenance dose of 3-5 grams daily