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8 Reasons for less weight loss with GLP1 RAs for T2D could include use of insulin or other obesity-promoting medications, concerns over hypoglycemia, decreased glycosuria, microbiome variation, genetic predisposition towards weight gain, and differences in endogenous GLP-1 pathways in the brain and other tissues
For details, see Retatrutide and Fatty Liver Disease
The Case For Oral GLP-1s And Its Limits One up-and-coming area is oral GLP-1 therapies
The expression of GLP-1s in genetically modified plants has been found to present a promising cost-effective approach for treating type 2 diabetes mellitus
