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Currently, orlistat is a commonly prescribed weight-loss medication in the UK, licensed for adults with a BMI 30 kg/m, or 28 kg/m with risk factors

Results The mean weight loss among patients prescribed GLP-1 analogue monotherapy at 12 months was 11.42 kg, SD 9.95 (9.6% TBWL)
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In STEP 1 [1] trials, 44% of patients experienced nausea and 30% developed diarrhea on semaglutide
