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GLP-1 receptor agonists are a class of medications that mimic the action of glucagon-like peptide-1, a naturally occurring hormone produced in the intestine
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However, loss of IL-1R signaling does not impact LPS-mediated GLP-1 secretion, as shown in Il1r / mice while neither LPS nor IL-1 stimulate GLP-1 secretion in Il6 / mice (Kahles et al., 2014)
It is important to note that compounded semaglutide and compounded tirzepatide are not FDA-approved
