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Megan Whitehouse Jun 12 4 min read GLP-1 medications such as semaglutide and tirzepatide are increasingly used for weight management and metabolic health in line with UK clinical guidance, such as NICE obesity management recommendations and NHS -supported prescribing frameworks

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The least-squares mean percentage change in body weight at 24 weeks in the retatrutide groups was -7.2% in the 1-mg group, -12.9% in the combined 4-mg group, -17.3% in the combined 8-mg group, and -17.5% in the 12-mg group, as compared with -1.6% in the placebo group

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