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The mean annual eGFR slope was significantly less steep (indicating a slower decrease) in the semaglutide group than the placebo group (2.19 vs 3.36 mL/min/1.73 m 2

Step four: establish a monitoring schedulethyroid labs every 812 weeks once semaglutide begins, with dose adjustments based on both weight loss progress and thyroid stability

Individuals with a personal or family history of medullary thyroid carcinoma or MEN2 are typically excluded from trials due to precautionary class-effect concerns

134 Here, we specifically focus on the understanding of GLP-1RA in another critical metabolic disorder: obesity
