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Preliminary program results are promising: ~1,500 clients have enrolled in the program since the program launched in April 2023, including: 61% of commercial employer-sponsored lives 17% of commercial health plan lives ** 67% of members meet smart logic criteria and do not require submission of a PA request 84% of PA requests result in denial, and 72% overall target fill rate *** ~$1B or ~$4.86 PMPM in client savings 3 These drugs are being studied in both weight- and non-weight-related conditions

Application of triple-probe microdialysis for fast pharmacokinetic/pharmacodynamic evaluation of dopamimetic activity of drug candidates in the rat brain

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This mechanism is central to emerging therapeutic strategies[1] designed to ensure robust insulin secretion and appetite suppression