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Use Numbing Creams: Over-the-counter numbing creams or gels applied to the area prior to the injection may help lessen the burning feeling
[DOI] [PMC free article] [PubMed] [Google Scholar] 421.Al-Sabah S., Donnelly D
Moreover, newer GLP-1 RAs and the long half-life of dual agonists (up to 7 days for Semaglutide) give rise to longer preoperative fasting period requirements and concerns of perioperative management of patients, even in case of treatment interruption [1517]

4 For example, ADA and KDIGO joint group has recommended that for patients with T2DM and CKD who do not achieve their glycemic target with metformin and/or an SGLT2i or cannot use them, a GLP-1RAs with proven cardiovascular benefit is recommended
