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Eli Lillys Next-Generation GLP-1R Agonist NaperiglipronStructure Revealed | Eli Lilly has disclosed the structure of its next-generation small molecule GLP-1R agonist, naperiglipron (LY3549492)

World Obesity Federation, World Obesity Atlas 2023 Unsurprisingly, weight loss medications have captured innovators attention as potential solutions, however, the obesity market has a history of many false dawns, as drugs in the past failed to deliver meaningful efficacy while some had serious safety issues, e.g., Fen-Phen, which was eventually withdrawn from the market due to cardiac risks3

Many people use drugs like Ozempic and Wegovy for weight loss, but stopping them carries rebound risks.
