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[1] [3] A 2024 review by the European Medicines Agency (EMA) and MHRA concluded that available evidence does not support a causal association between GLP-1 receptor agonists (including semaglutide) and suicidal thoughts or behaviour
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the placebo also lost considerably more weight, with those who received the study medication losing an average of more than 13% of their body weight compared to a nearly 3% reduction in body weight for volunteers who received the placebo
The FLOW trial further demonstrated that semaglutide reduced cardiovascular risk regardless of baseline CKD severity [114]
